Hematoma Evacuation

In adult patients (≥18 years) with spontaneous supratentorial intracerebral hemorrhage (volume 10-60 mL, GCS 5-12, pre-ICH mRS 0-1), does early surgical hematoma evacuation (within 24 hours) plus medical care, compared with initial conservative medical care alone, improve functional outcome (mRS score) at 180 days?

In adult patients with spontaneous superficial lobar intracerebral hemorrhage (10-100 mL, GCS ≥6T/7), does a policy of early surgical hematoma evacuation by craniotomy plus best medical treatment, compared with best medical treatment alone (with delayed surgery if needed), improve outcome at 6 months?

In adult patients with spontaneous supratentorial intracerebral hemorrhage, does a policy of early surgical hematoma evacuation plus best medical treatment, compared with best medical treatment alone (with delayed surgery if needed), improve outcome at 6 months?

In adult patients (18-80 years) with spontaneous supratentorial intracerebral hemorrhage (volume ≥30 mL, GCS 4-14), does minimally invasive catheter evacuation followed by alteplase instillation, compared with standard medical care alone, improve functional outcome (mRS 0-3) at 365 days?

In adult patients (18-80 years) with spontaneous supratentorial intracerebral hemorrhage (lobar or basal ganglia, volume 30-80 mL, GCS 5-14), does early minimally invasive parafascicular surgery (MIPS) plus medical management, compared with medical management alone, improve functional outcome (utility-weighted mRS) at 180 days?