Anti-fibrinolytic Therapy

Published in The Lancet
Intracerebral HemorrhageHemostasis Tranexamic Acid Anti-fibrinolytic Therapy

In adult patients with acute spontaneous intracerebral hemorrhage treated within 8 hours of onset, does tranexamic acid, compared with placebo, improve functional outcome (mRS score) at 90 days?

Published in The Lancet Neurology
Intracerebral HemorrhageHemostasis Tranexamic Acid Anti-fibrinolytic Therapy Hematoma Expansion Imaging Biomarkers

In adult patients with acute spontaneous intracerebral hemorrhage and a CT angiography spot sign, treated within 4.5 hours of onset, does tranexamic acid, compared with placebo, reduce hematoma expansion at 24 hours?