Acute Ischemic Stroke

SHINE

Published in JAMA (Journal of the American Medical Association)
Acute Ischemic StrokeGlucose Control Insulin Therapy Supportive Care Ischemic Stroke Management

In adult patients with acute ischemic stroke and hyperglycemia, does intensive glucose control (target 80-130 mg/dL with IV insulin) compared with standard glucose control (target 80-179 mg/dL with subcutaneous insulin) improve functional outcome at 90 days?

INTREPID

Published in JAMA (Journal of the American Medical Association)
Acute Ischemic Stroke Intracerebral Hemorrhage Subarachnoid HemorrhageTemperature Management Fever Prevention Neurocritical Care Supportive Care

In critically ill adult patients with acute vascular brain injury (ischemic stroke, ICH, or SAH), does active fever prevention targeting 37.0°C using an automated surface device, compared with standard reactive fever treatment, improve functional outcome at 3 months?

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